Hoofdstuk IV: Genetische manipulatie

1. P. Berg, “Dissections and Reconstructions of Genes and Chromosomes ” Science 213 (1981), pp. 296-303.
2. D. Gershon, “First experiment approved,” Nature 346 (1990), p. 402; E. Marshall, “Jury still out on pioneering treatment,” Science 269 (1995), p. 1051.
3. E. Marshall, “The trouble with vectors,” Science 269 (1995), p. 1052.
4. D. Gershon, “Cancer trial starts,” Nature 349 (1991), p. 445; E. Marshall, “Gene therapy’s growing pains,” Science 269 (1995), p. 1053; cf Si.-Yi Chen, A-G. Yang, et. Al., “Potent antitumour activity of a new class of tumour-specific killer cells, “Nature 385 (1997) pp. 78-80.
5. E. Boné, “Le génie génétique au prisme de l’éthique,” Revue théologique de Louvain 17 (1986), pp. 172-173; O. Höffe, “Drei Diskussionsbemerkungen zur Ethik der Genmanipulation, in H. Lenk Humane Experimente, Genbiologie und Psychologie, München/Paderborn/Wien/Zürich: Wilhelm Fink/Ferdinand Schöningh, 1985 (Ethik der Wissenschaften, Bd 3), p. 63; J. Piegsa, “Genmanipulation – Schöpfungsauftrag oder gotteslästerliche Hybris?, Theologie der Gegenwart 28 (1985), pp. 231-232; J. Reiter, Möglichkeiten und Grenzen der Gentechnologie,” Theologie der Gegenwart 28 (1985), p. 24; Ethische Implikationen der Gen-Forschung,” Slimmen der Zeit 202 (1984), pp. 443-444; Ethische Grenzen für den Menschen als Forscher und Schöpfer,” Theologie der Gegenwart32 (1989), pp. 118-119.
6. Vgl. I.J.M de Boer, “Toepassing van klonen in de melkveefokkerij. Ethische aspecten,” in: Ethiek uit het veld, Wageningen: Koninklijk Genootschap voor Landbouwwetenschap, 1994, pp.50-51.
7. W.J. Eijk, The ethical problems of genetic engineering of human beings, Kerkrade, 1990 (academIsch proefschrift, faculteit voor filosofie, Pontificia Universitas S. Thomae de Urbe, Rome).
8. Ibid., pp. 85-91.
9. R.D. Palmiter, R.L. Brinster, et al., “Dramatic growth of mice that develop from eggs microinjected with metallothionein-growth hormone fusion genes,” Nature 300 (1982), pp. 611-615; R.D. Palmiter, G. Norstedt, et al., “Metallothionein-Human GH Fusion Genes Stimulate Growth of Mice,” Science 222 (1983), pp. 809-814.
10. R. Scott Struthers, W.W. Vale, et al., “Somatotroph hypoplasia and dwarfism in transgenic mice expressing a non-phosphorylatable CREB mutant,” Nature 350 (1991) pp 622-624.
11. G.E. Lamming, “Regulating growth of animals,” Nature 336 (1988), p. 20; JL. Marx, GeneWatcher’s Feast Served UP in Toronto,” Science 242 (1988), pp. 32-33; V.G. Pursel, CA. Pinkert, Genetic Engineering of Livestock,” Science 244 (1989) pp. 1281-1288.
12. F. Costantini, K. Chada J. Magram, “Correction of Murine ß-Thalassaemia by Gene Transfer into the Germ Line,” Science 233 (1986), pp. 1192-1194.
13. Genen en grenzen, Een christen-democratische bijdrage aan de discussie over de gentechnologie, Den Haag: Wetenschappelijk Instituut voor het CDA, 1992, p. 23
14. “Biotech-bedrijf vraagt gratie voor stier Herman,” Trouw, 9 mei 1996, p. 1 en 7.
15. N. Williams, “Pig-human transplants barred for now,” Science 275 (1997),24 januari, p. 473
16. Donum Vitae II. B, 4-5.
17. Zie dit boek pp. 43.
18. V.G. Pursel, CA. Pinkert, “Genetic Engineering of Livestock,” op. cit, p. 1282.
19. JD. McNeish, W.J. Scott, S. Steven Porter, “Legless, a Novel Mutation Found in PHT1-1 Transgenic Mice,” Science 241 (1988), pp. 837-839. Vgl. R.P. Woychik, T.A. Stewart, et al., “An inherited limb deformity created by insertional mutagenesis in a transgenic mouse,” Nature 318 (1985), pp. 36-40.
20. A. Schnieke, Kl. Harbers, R. Jaenisch, “Embryonic lethal mutation in mice induced by retrovirus insertion into the α1(I) collagen gene,” Nature 304 (1983) pp. 315-320; Kl. Kratochwil, K. von der Mark, “Retrovirus-Induced Insertional Mutation in Mov13 Miee Affects Collagen I Expression in a Tissue-Specific Manner,” Cell 57 (1989), pp. 807-816.
21. Zie M.R. Capecchi, “Altering the Genome by Homologous Recombination “, Science 244 (1989), p. 1289; R.S. Johnson, M. Sheng, et al., “Targeting of Nonexpressed Genes in Embryonic Stem Cells Via Homologous Recombination,” Science 245 (1989), pp. 1234-1236; P. Hasty, R. Ramirez-Solis, et al., “Introduction of a subtle mutation into the Hox-2.6 locus in embryonic stem cells,” Nature 350 (1991), pp. 243-246.
22. B.K. Zimmerman, “Human germ-line therapy: the case for its development and use,” Joumal of medicine and philosophy 16 (1991), p. 602.
23. Vgl. M. Lavitrano, A. Camaioni, et al., “Sperm Cells as Vectors for Introducing Foreign DNA into Eggs: Genetic Transformation of Mice,” Cell 57 (1989), pp. 717-723: R.L. Brinster, E.P. Sandgren, et al., “No Simple Solution for Making Transgenic Mice,” Cell 59 (1989), pp. 239-241. Cfr. J. Maddox, “Transgenic route runs into sand,” Nature 341 (1989), p. 686; M. Barinaga, “Gene- Transfer Method Faits Test”, Science 246 (1989), p. 446.
24. A. Coghlan, “Outrage greets patent on designer sperm,” New Scientist (1994 ), 9 april, pp. 4-5; “Patents for eugenics,” Nature 368 (1994), p. 572.
25. D.S. Rubenstein, D.C. Thomasma, E.A. Schon, M.J. Zinaman, “Germ-line therapy to cure mitochondrial disease: protocol and ethics of in vitro ovum nuclear transplantation,” Cambridge Quarterly of Healthcare Ethics 4 (1995), pp. 316-399, speciaal 321-322.
26. B.K. Zimmerman, “Human germ-line therapy: the case for its development and use,” op. cit., pp. 594 en 596-598.
27. N.J. Zohar, “Prospects for “genetic therapy”‘ – Can a person benefit from being altered?,” Bioethics 5 (1991), pp. 275-288.
28. I. Persson, “Genetic therapy, identity and the person-regarding reasons,” Bioethics 9 (1995), pp. 16-31.
29. Zie voor een filosofische analyse van de verschillende betekenissen van de term identiteit R.L. Fetz, “Personbegriffund Identitätstheorie,” Freiburger Zeitschriftfür Philosophie und Theologie 35 (1988), pp. 69-106.
30. W.J. Eijk, The ethical problems of genetic engineering of human beings, op. cit., pp. 188-200.
31. N. Agar, “Designing babies: morally permissible ways to modify the human genome,” Bioethics 9 (1995), pp. 1-15.
32. H.T. Engelhardt, The foundations of bioethics, New York/Oxford: Oxford University Press, 1986, pp. 377-385.
33. D.J. Kevles, “Eugenics: historica1 aspects,’ in: Encyclopedia of Bioethics, W.T. Reich (ed.), New York/London: Macmillan Library Reference USA/Simon & Schuster and Prentice Hall International, 1995 (2e ed.), vol. 2, p. 767; vgl. “China’s misconception of eugenics,” Nature 367 (1994), p. 1-2; “D. Dickson, “Concern grows over China’s plans to reduce number of ‘inferior births’,” ibid., p. 3; Cl. O’Brien, “China urged to delay ‘eugenics’ law … ,” Nature 383 (1996), September 19, p. 204.
34. P. Ramsey, Fabricated Man. The Ethics of Genetic Control, New Haven/London: Yale University Press, 1970, pp. 123-130.
35. D. Weatherall, “Treatment of the future,’ Nature 334 (1988), p. 305.

Overgenomen met toestemming van uitgeverij Colomba.